| Creator | Development started | First public release | Latest stable version | Stable release date | Cost | License | Notes |
| ADMB | David Fournier, ADMB Project | 1989 | 1990 | 12.0 | | | BSD 3-clause License | Automatic differentiation makes it well suited to complex minimization problems |
| Analytica | Lumina Decision Systems | 1982 | | 4.6 | | | Proprietary | A numerical modeling environment with a declarative and visual programming language based on influence diagrams. |
| Ch | SoftIntegration | | | 7.5.1 | | | Proprietary | C/C++ based numerical computing and graphical plotting |
| DADiSP | DSP Development | 1984 | 1987 | 6.7 B02 | | | Proprietary | Numeric computations for science and engineering featuring a spreadsheet like interface. |
| Dyalog APL | Dyalog Ltd. | 1981 | 1983 | 18.0 | | | Proprietary | A modern dialect of APL, enhanced with features for functional and object-oriented programming. |
| Euler Math Toolbox | René Grothmann | 1987 | 1988 | 2020-05-06 | | | GPL | Also a computer algebra system through interface with Maxima |
| Fityk | Marcin Wojdyr | | 2002 | 1.3.1 | | | GPL | interactive graphics, scriptable, specialized in curve fitting and peak fitting, 2D only |
| FlexPro | Weisang GmbH | n/a | 1991 | 2017 | 2017 | | Proprietary | Dynamic, interactive 2D/3D diagrams, programmable, VBA, high performances, multicore compatible, large data sets. |
| FreeMat | Samit Basu | | 2004 | 4.2 | | | GPL | Codeless interface to external C, C++, and Fortran code. Mostly compatible with MATLAB. |
| GAUSS | Aptech Systems | | 1984 | 19 | | | Proprietary | |
| GNU Data Language | Marc Schellens | | 2004 | 0.9.7 | | | GPL | Aimed as a drop-in replacement for IDL/PV-WAVE |
| IBM SPSS Statistics | Norman H. Nie, Dale H. Bent, and C. Hadlai Hull | | 1968 | 23.0 | | | Proprietary | Primarily for statistics |
| GNU MCSim | Frederic Y. Bois & Don Maszle | 1991 | 1993 | 6.0.0 | | | GPL | General simulation and Monte Carlo sampling software |
| GNU Octave | John W. Eaton | 1988 | 1993 | 5.2.0 | | | GPL | General numerical computing package with lots of extension modules. Syntax mostly compatible with MATLAB |
| IGOR Pro | WaveMetrics | 1986 | 1988 | 8.00 | | | Proprietary | interactive graphics, programmable, 2D/3D, used for science and engineering, large data sets. |
| J | Jsoftware | 1989 | 1990 | J806 | | | GPL | online access to: J Application Library |
| Julia | Jeff Bezanson, Stefan Karpinski, Viral B. Shah, and Alan Edelman | 2009 | 2012 | 1.4.0 | | | MIT License | A fast, high-level numerical computing language. |
| LabPlot | Stefan Gerlach | 2001 | 2003 | 2.6.0 | | | GPL | data analysis, nonlinear curve fitting in 2D, data picking from images, live data plotting |
| LabVIEW | National Instruments | 1985 | 1986 | 2016 | | | Proprietary | Graphical, and textual through formula nodes, mathscript and.m file scripts |
| Maple | Maplesoft | 1980 | 1982 | | | | Proprietary | Mainly a computer algebra system |
| Mathcad | Parametric Technology Corporation | 1985 | 1986 | 15.0 ; Prime 4.0 | | | Proprietary | |
| Mathematica | Wolfram Research | 1986 | 1988 | | | | Proprietary | Also computer algebra system |
| MATLAB | MathWorks | late 1970s | 1984 | 9.8 | | | Proprietary | Numerical computation and simulation with extended 2D/3D visualization. Emphasis on vectorised processing. |
| Maxima | MIT Project MAC and Bill Schelter et al. | 1967 | 1982 | 5.41.0 | | | GPL | Mainly a computer algebra system |
| MLAB | Civilized Software, Inc. | 1970, 1985 | 1972, 1988, 1993 | 2015 | | | Proprietary | Numerical and Statistical computation for Scientific Applications, e.g. Chemical Kinetics. ODE Solving and Curve-Fitting. Symbolic Differentiation, Survival Analysis, Cluster Analysis, 2D/3D Graphics. |
| Origin | OriginLab | | 1991 | 2019b | April 24, 2019 | | Proprietary | Integrated data analysis graphing software for science and engineering. Flexible multi-layer graphing framework. 2D, 3D and statistical graph types. Built-in digitizing tool. Analysis with auto recalculation and report generation. Built-in scripting and programming languages. |
| Perl Data Language | Karl Glazebrook | 1996 | c. 1997 | 2019 | | | Artistic License | Used for astrophysics, solar physics, oceanography, biophysics, and simulation. 2D plotting via PGPLOT, PLPlot bindings; 3D via GL. |
| PSPP | Ben Pfaff | 1990s | 1990s | 1.2.0 | | | GPL v.3 or later | FOSS statistics program, intended as an alternative to IBM SPSS Statistics. |
| R | R Foundation | 1997 | 1997 | 3.6.3 | | | GPL | Primarily for statistics, but there are many interfaces to open-source numerical software |
| SageMath | William Stein | | 2005 | | | | GPL | Programmable, includes computer algebra, 2D+3D plotting. Interfaces to many open-source and proprietary software. Web based interface HTTP or HTTPS |
| SAS | Anthony Barr and James Goodnight | 1966 | 1972 | 9.4 | | | Proprietary | Mainly for statistics |
| SequenceL | Texas Multicore Technologies | 1989 | 2012 | 2.4 | | | Proprietary | Functional programming language and tools. |
| S-Lang | John E. Davis | | 1992 | 2.3.0 | | | GPL, Artistic License | Available as a standalone and embedded interpreter |
| Scilab | ESI Group
Was:Inria | 1990 | 1994 | 6.1.0 | 25 February 2020 | | GPL | Programmable, direct support of 2D+3D plotting. Interfaces to many other software packages. Interfacing to external modules written in C, Java, Python or other languages. Language syntax similar to MATLAB. Used for numerical computing in engineering and physics. |
| Sysquake | Calerga | | 1998 | 5.0 | | | Proprietary | interactive graphics |
| TK Solver | Universal Technical Systems, Inc. | late 1970s | 1982 | 6.0.152 | | | Proprietary | Numerical computation and rule-based application development |
| VisSim | Visual Solutions | | 1989 | 10.1 | | | Proprietary | Visual Language for simulation and Model Based Design. Used in business, science and engineering. Performs complex scalar or matrix based ODE solving with parametric optimization. Has 2D and 3D plotting, 3D animation, and state transition built in. |
| Yorick | n/a | n/a | n/a | 9 | | | GPL | Programmable, callable 2D+3D plotting. Language syntax similar to C. Interfacing to other software packages via C calls. |
